Mr Markides was born in Nicosia in 1943. He graduated in 1966 with first-class honours from the Law School of the University of Athens. In 1970 he was called to the Bar of the Middle Temple Inn, England.

Mr Markides practised law in Cyprus from September 1971 until February 1995. On 1 February 1995, he was appointed to the post of Attorney General of the Republic of Cyprus. He served as Attorney General until 23 April 2003. Since then he has resumed practising law.

Between 1979 and 1993, Mr Markides was the Secretary General and from 1993 to 1995, the Deputy President of the Democratic Rally political party – one of the two strongest political parties of Cyprus. Between 1985 and 1995, he was twice elected and served as a member of the House of Representatives of the Republic of Cyprus. In 2003, he was one of the candidates for President of the Republic.

From 1985 to 1990, Mr Markides was a co-editor with his wife, Hermione Markides, of the Cyprus Law Reports. Since 2001, he has been a lecturer and examiner on behalf of the legal council of pupil advocates in respect of constitutional law and civil procedure law. He is also a visiting professor of constitutional law at the University of Nicosia. Mr Markides is also one of the four Cypriot members of the Permanent Court of Arbitration.

Mr Markides is currently acting as arbitrator, co-arbitrator or umpire in five pending arbitrations, while last year he issued his award as single arbitrator in a prominent case between the Republic of Cyprus and a company that transported 50,000 tonnes of water from Greece to Cyprus in 2008 and 2009.

Markides, Markides & Co is now the only shareholder of Markides, Markides & Co LLC, a company with liability limited by shares; established in December 2011, it began business on 1 January 2012.